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Article

FKBP5 polymorphisms moderate the influence of adverse life events on the risk of anxiety and depressive disorders in preschool children.

Journal of psychiatric research - 1 Jan 2016

Scheuer Sandra, Ising Marcus, Uhr Manfred, Otto Yvonne, von Klitzing Kai, Klein Annette Maria

Abstract excerpt

FKBP5 is thought to be involved in the pathogenesis of stress-related disorders. Studies have shown that FKBP5 genotypes moderate the risk of post-traumatic stress disorder and depression in traumatized adults. We aimed to replicate this finding in a sample of preschool children. Parents of preschoolers (N = 186) were interviewed using the Preschool Age Psychiatric Assessment (PAPA) to evaluate the presence of...

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Source

Identifiers

PMID: 26521051
DOI: 10.1016/j.jpsychires.2015.10.009

Genes

FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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