Article
BRI2 and BRI3 are functionally distinct phosphoproteins.
Cellular signalling - 1 Jan 2016
Martins Filipa, Rebelo Sandra, Santos Mariana, Cotrim Cândida Zita, da Cruz e Silva Edgar F, da Cruz e Silva Odete A B
Abstract excerpt
Three BRI protein family members have been identified. Among these are BRI3 and BRI2, the latter is associated with Familial Danish and Familial British dementias. 'In silico' sequence analysis identified putative PP1 binding sites in BRI2 and BRI3. This is singularly important, given that protein phosphorylation is a major mechanism regulating intracellular processes. Protein phosphatase 1 (PP1) interacting...
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