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Article

Engineering Escherichia coli for fumaric acid production from glycerol.

Bioresource technology - 1 Dec 2014

Li Ning, Zhang Bo, Wang Zhiwen, Tang Ya-Jie, Chen Tao, Zhao Xueming

Abstract excerpt

The evolved mutant Escherichia coli E2 previously developed for succinate production from glycerol was engineered in this study for fumaric acid production under aerobic conditions. Through deletion of three fumarases, 3.65g/L fumaric acid was produced with the yield of 0.25mol/mol glycerol and a large amount of acetate was accumulated as the main byproduct. In order to reduce acetate production several...

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Identifiers

PMID: 25463785
DOI: 10.1016/j.biortech.2014.09.147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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