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Article

Serum bilirubin and ferritin levels link heme oxygenase-1 gene promoter polymorphism and susceptibility to coronary artery disease in diabetic patients.

Diabetes care - 1 Aug 2008

Chen Ying-Hwa, Chau Lee-Young, Chen Jaw-Wen, Lin Shing-Jong

Abstract excerpt

OBJECTIVE: Heme oxygenase (HO) leads to the generation of free iron, carbon monoxide, and bilirubin. A length polymorphism of GT repeats in the promoter of human HO-1 gene has been shown to modulate gene transcription. The aim of this study was to assess the association of the length of (GT)(n) repeats in the HO-1 gene promoter with serum bilirubin, markers of iron status, and the development of coronary artery...

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Identifiers

PMID: 18443197
DOI: 10.2337/dc07-2126
PMCID: PMC2494663

Genes

CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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