Article
Risk Genes of Inflammatory Bowel Disease in Asia: What Are the Most Important Pathways Affected?
Digestive diseases (Basel, Switzerland) - 1 Jan 2016
Guo Changcun, Wu Kaichun
Abstract excerpt
Genetic factors play an important role in the pathogenesis of inflammatory bowel disease (IBD), and IBD is now recognized as a complex disease that results from interplay between genetic and environment factors. To date, over 160 IBD-susceptible loci have been identified using genome-wide association studies (GWAS). The risk genes identified in these studies are involved in various pathways in innate and adaptive...
Topics
- Adaptive Immunity
- Asia
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
- Inflammatory Bowel Diseases
- Risk Factors
