Article
Population-specific susceptibility to Crohn's disease and ulcerative colitis; dominant and recessive relative risks in the Japanese population.
Annals of human genetics - 1 Mar 2010
Nakagome Shigeki, Takeyama Yasuaki, Mano Shuhei, Sakisaka Shotaro, Matsui Toshiyuki, Kawamura Shoji, Oota Hiroki
Abstract excerpt
Crohn's disease (CD), a type of chronic inflammatory bowel disease (IBD), is commonly found in European and East Asian countries. The calculated heritability of CD appears to be higher than that of ulcerative colitis (UC), another type of IBD. Recent genome-wide association studies (GWAS) have identified more than thirty CD-associated genes/regions in the European population. In the East Asian population,...
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