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Article

Identification of type 2 diabetes subgroups through topological analysis of patient similarity.

Science translational medicine - 28 Oct 2015

Li Li, Cheng Wei-Yi, Glicksberg Benjamin S, Gottesman Omri, Tamler Ronald, Chen Rong, Bottinger Erwin P, Dudley Joel T

Abstract excerpt

Type 2 diabetes (T2D) is a heterogeneous complex disease affecting more than 29 million Americans alone with a rising prevalence trending toward steady increases in the coming decades. Thus, there is a pressing clinical need to improve early prevention and clinical management of T2D and its complications. Clinicians have understood that patients who carry the T2D diagnosis have a variety of phenotypes and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26511511
DOI: 10.1126/scitranslmed.aaa9364
PMCID: PMC4780757

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