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Article

POCUS: mining genomic sequence annotation to predict disease genes.

Genome biology - 1 Jan 2003

Turner Frances S, Clutterbuck Daniel R, Semple Colin A M

Abstract excerpt

Here we present POCUS (prioritization of candidate genes using statistics), a novel computational approach to prioritize candidate disease genes that is based on over-representation of functional annotation between loci for the same disease. We show that POCUS can provide high (up to 81-fold) enrichment of real disease genes in the candidate-gene shortlists it produces compared with the original large sets of...

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Identifiers

PMID: 14611661
DOI: 10.1186/gb-2003-4-11-r75
PMCID: PMC329128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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