Article

GenoWAP: Post-GWAS Prioritization Through Integrated Analysis of Genomic Functional Annotation

2015-05-20

Abstract excerpt

Genome-wide association study (GWAS) has been a great success in the past decade. However, significant challenges still remain in both identifying new risk loci and interpreting results. Bonferroni-corrected significance level is known to be conservative, leading to insufficient statistical power when the effect size is moderate at risk locus. Complex structure of linkage disequilibrium also makes it challenging t...

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Literature Corpus work: d7c1bcf4-a66b-5654-9b23-87c2542750ff
DOI: 10.1101/019539

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