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Article

Systematic validation of specific phenotypic markers for in vitro polarized human macrophages.

Journal of immunological methods - 31 Jan 2012

Ambarus C A, Krausz S, van Eijk M, Hamann J, Radstake T R D J, Reedquist K A, Tak P P, Baeten D L P

Abstract excerpt

BACKGROUND: Polarization of macrophages by specific micro-environmental conditions impacts upon their function following subsequent activation. This study aimed to systematically validate robust phenotypic markers for in vitro polarized human macrophages in order to facilitate the study of macrophage subsets in vivo. METHODS: Human peripheral blood monocytes were polarized in vitro with IFN-γ, IL-4, or IL-10....

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PMID: 22075274
DOI: 10.1016/j.jim.2011.10.013

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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