Article
Joint Effect of Genotypic and Phenotypic Features of Reproductive Factors on Endometrial Cancer Risk.
Scientific reports - 26 Oct 2015
Wang Zhanwei, Risch Harvey, Lu Lingeng, Irwin Melinda L, Mayne Susan, Schwartz Peter, Rutherford Thomas, De Vivo Immaculata, Yu Herbert
Abstract excerpt
Prolonged estrogen exposure is believed to be the major cause of endometrial cancer. As possible markers of estrogen exposure, various menstrual and reproductive features, e.g., ages at menarche and menopause, are found to be associated with endometrial cancer risk. In order to assess their combined effects on endometrial cancer, we created the total number of menstrual cycles (TNMC) that a woman experienced...
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