Article
Body Mass Index Genetic Risk Score and Endometrial Cancer Risk.
PloS one - 1 Jan 2015
Prescott Jennifer, Setiawan Veronica W, Wentzensen Nicolas, Schumacher Fredrick, Yu Herbert, Delahanty Ryan, Bernstein Leslie, Chanock Stephen J, Chen Chu, Cook Linda S, Friedenreich Christine, Garcia-Closas Monserrat, Haiman Christopher A, Le Marchand Loic, Liang Xiaolin, Lissowska Jolanta, Lu Lingeng, Magliocco Anthony M, Olson Sara H, Risch Harvey A, Shu Xiao-Ou, Ursin Giske, Yang Hannah P, Kraft Peter, De Vivo Immaculata
Abstract excerpt
Genome-wide association studies (GWAS) have identified common variants that predispose individuals to a higher body mass index (BMI), an independent risk factor for endometrial cancer. Composite genotype risk scores (GRS) based on the joint effect of published BMI risk loci were used to explore whether endometrial cancer shares a genetic background with obesity. Genotype and risk factor data were available on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
