Article
Impact of Nonsynonymous Single-Nucleotide Variations on Post-Translational Modification Sites in Human Proteins.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Gulzar Naila, Dingerdissen Hayley, Yan Cheng, Mazumder Raja
Abstract excerpt
Post-translational modifications (PTMs) are covalent modifications that proteins might undergo following or sometimes during the process of translation. Together with gene diversity, PTMs contribute to the overall variety of possible protein function for a given organism. Single-nucleotide polymorphisms (SNPs) are the most common form of variations found in the human genome, and have been found to be associated...
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