Article
AWESOME: a database of SNPs that affect protein post-translational modifications.
Nucleic acids research - 8 Jan 2019
Yang Yang, Peng Xiating, Ying Pingting, Tian Jianbo, Li Jiaoyuan, Ke Juntao, Zhu Ying, Gong Yajie, Zou Danyi, Yang Nan, Wang Xiaoyang, Mei Shufang, Zhong Rong, Gong Jing, Chang Jiang, Miao Xiaoping
Abstract excerpt
Protein post-translational modifications (PTMs), including phosphorylation, ubiquitination, methylation, acetylation, glycosylation et al, are very important biological processes. PTM changes in some critical genes, which may be induced by base-pair substitution, are shown to affect the risk of diseases. Recently, large-scale exome-wide association studies found that missense single nucleotide polymorphisms...
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