Article
Human proteins with target sites of multiple post-translational modification types are more prone to be involved in disease.
Journal of proteome research - 6 Jun 2014
Huang Qianli, Chang Jinhui, Cheung Man Kit, Nong Wenyan, Li Lei, Lee Ming-Tsung, Kwan Hoi Shan
Abstract excerpt
Many proteins can be modified by multiple types of post-translational modifications (Mtp-proteins). Although some post-translational modifications (PTMs) have recently been found to be associated with life-threatening diseases like cancers and neurodegenerative disorders, the underlying mechanisms remain enigmatic to date. In this study, we examined the relationship of human Mtp-proteins and disease and...
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