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Article

Adaptive Evolution Is Substantially Impeded by Hill-Robertson Interference in Drosophila.

Molecular biology and evolution - 1 Feb 2016

Castellano David, Coronado-Zamora Marta, Campos Jose L, Barbadilla Antonio, Eyre-Walker Adam

Abstract excerpt

Hill-Robertson interference (HRi) is expected to reduce the efficiency of natural selection when two or more linked selected sites do not segregate freely, but no attempt has been done so far to quantify the overall impact of HRi on the rate of adaptive evolution for any given genome. In this work, we estimate how much HRi impedes the rate of adaptive evolution in the coding genome of Drosophila melanogaster. We...

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Identifiers

PMID: 26494843
DOI: 10.1093/molbev/msv236
PMCID: PMC4794616

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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