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Article

The relation between recombination rate and patterns of molecular evolution and variation in Drosophila melanogaster.

Molecular biology and evolution - 1 Apr 2014

Campos José L, Halligan Daniel L, Haddrill Penelope R, Charlesworth Brian

Abstract excerpt

Genetic recombination associated with sexual reproduction increases the efficiency of natural selection by reducing the strength of Hill-Robertson interference. Such interference can be caused either by selective sweeps of positively selected alleles or by background selection (BGS) against deleterious mutations. Its consequences can be studied by comparing patterns of molecular evolution and variation in genomic...

Topics

Animals
Chromosomes, Insect
Crossing Over, Genetic
Drosophila melanogaster
Evolution, Molecular
Female
Genome, Insect
Heterochromatin
Male
Models, Genetic
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombination, Genetic

Selection, Genetic

X Chromosome

Source

Open in PubMed Open full text

Identifiers

PMID: 24489114
DOI: 10.1093/molbev/msu056
PMCID: PMC3969569

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