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Article

Hitchhiking effects of recurrent beneficial amino acid substitutions in the Drosophila melanogaster genome.

Genome research - 1 Dec 2007

Andolfatto Peter

Abstract excerpt

Several recent studies have estimated that a large fraction of amino acid divergence between species of Drosophila was fixed by positive selection, using statistical approaches based on the McDonald-Kreitman test. However, little is known about associated selection coefficients of beneficial amino acid mutations. Recurrent selective sweeps associated with adaptive substitutions should leave a characteristic...

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Identifiers

PMID: 17989248
DOI: 10.1101/gr.6691007
PMCID: PMC2099584

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Source receipt: pubmed, retrieved 7 Sept 2026.

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