Article
Recombination Rate Variation Modulates Gene Sequence Evolution Mainly via GC-Biased Gene Conversion, Not Hill-Robertson Interference, in an Avian System.
Molecular biology and evolution - 1 Jan 2016
Bolívar Paulina, Mugal Carina F, Nater Alexander, Ellegren Hans
Abstract excerpt
The ratio of nonsynonymous to synonymous substitution rates (ω) is often used to measure the strength of natural selection. However, ω may be influenced by linkage among different targets of selection, that is, Hill-Robertson interference (HRI), which reduces the efficacy of selection. Recombination modulates the extent of HRI but may also affect ω by means of GC-biased gene conversion (gBGC), a process leading...
Topics
- Animals
- Base Composition
- Birds
- Evolution, Molecular
- Gene Conversion
- Genetic Variation
- Models, Genetic
- Mutation
- Polymorphism, Single Nucleotide
- Recombination, Genetic
- Selection, Genetic