Article
Analysis of Niemann-Pick C1-like 1 (NPC1L1) genetic polymorphisms and haplotypes in Chinese Han population.
Die Pharmazie - 1 Sept 2015
Lou Xiao-Ya, Qin Chong-Zhen, Bao Mei-Hua, Hu Dong-Li, Chen Feng, Sun Hong, Chen Yao, Guo Dong, Zhang Wei, Cheng Yu, Zhou Hong-Hao
Abstract excerpt
Niemann-Pick C1-like 1 (NPC1L1i) protein is the key transporter responsible for dietary cholesterol absorption. Recent studies indicated that several functional polymorphisms of NPC1L1 were associated with coronary heart disease (CHD) and response to ezetimibe therapy. The aim of the present study was to analyze the allele frequency and haplotype distribution of NPC1L1 polymorphisms in Chinese Hans and to compare...
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