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Article

Identification and characterization of NPC1L1 variants in Uygur and Kazakh with extreme low-density lipoprotein cholesterol.

Biochemical and biophysical research communications - 28 Oct 2016

Yuan Qinghua, Fu Zhenyan, Wei Jian, Li Pei-Shan, Miao Hong-Hua, Qu Yu-Xiu, Xu Jie, Qin Jie, Li Bo-Liang, Song Bao-Liang, Ma Yitong

Abstract excerpt

BACKGROUND: Plasma levels of low-density lipoprotein cholesterol (LDL-C) are a major risk factor for cardiovascular disease and are influenced by both heredity and dietary habits. The Niemann-Pick C1 like 1 (NPC1L1) protein mediates efficient dietary cholesterol absorption and contributes to variations in human LDL-C levels. METHODS: In the present study, using high throughput sequencing we identified three...

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PMID: 27697530
DOI: 10.1016/j.bbrc.2016.09.164

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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