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Article

Myeloproliferative neoplasms: A decade of discoveries and treatment advances.

American journal of hematology - 1 Jan 2016

Tefferi Ayalew

Abstract excerpt

Myeloproliferative neoplasms (MPN) are clonal stem cell diseases, first conceptualized in 1951 by William Dameshek, and historically included chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). In 1960, Nowell and Hungerford discovered an invariable association between the Philadelphia chromosome (subsequently shown to harbor the causal BCR-ABL1...

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Source

Identifiers

PMID: 26492355
DOI: 10.1002/ajh.24221

Genes

CALR
JAK2
MPL
ABL1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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