Article
Guidelines for the management of myeloproliferative neoplasms.
The Korean journal of internal medicine - 1 Nov 2015
Choi Chul Won, Bang Soo-Mee, Jang Seongsoo, Jung Chul Won, Kim Hee-Jin, Kim Ho Young, Kim Soo-Jeong, Kim Yeo-Kyeoung, Park Jinny, Won Jong-Ho
Abstract excerpt
Polycythemia vera, essential thrombocythemia, and primary myelofibrosis are collectively known as 'Philadelphia-negative classical myeloproliferative neoplasms (MPNs).' The discovery of new genetic aberrations such as Janus kinase 2 (JAK2) have enhanced our understanding of the pathophysiology of MPNs. Currently, the JAK2 mutation is not only a standard criterion for diagnosis but is also a new target for drug...
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