Article
Independent predictive roles of eotaxin Ala23Thr, paraoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on cardiac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients.
Diabetic medicine : a journal of the British Diabetic Association - 1 Apr 2010
Wang Y, Luk A O Y, Ma R C W, So W Y, Tam C H T, Ng M C Y, Yang X, Baum L, Lam V, Tong P C Y, Chan J C N
Abstract excerpt
AIMS: To examine the independent and joint effects of multiple genetic variants on a cardiac end-point in an 8-year prospective study of a Chinese diabetic cohort. METHODS: Seventy-seven single nucleotide polymorphisms (SNPs) of 53 candidate genes for inflammation, thrombosis, vascular tone regulation and lipid metabolism were genotyped in 1297 Chinese patients with no prior history of coronary heart disease...
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