Gene Expression-Genotype Analysis Implicates GSDMA, GSDMB, and LRRC3C as Contributors to Inflammatory Bowel Disease Susceptibility.

doi:10.1155/2015/834805

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Article

Gene Expression-Genotype Analysis Implicates GSDMA, GSDMB, and LRRC3C as Contributors to Inflammatory Bowel Disease Susceptibility.

BioMed research international - 1 Jan 2015

Söderman Jan, Berglind Linda, Almer Sven

Abstract excerpt

To investigate the biological foundation of the inflammatory bowel disease (IBD), ulcerative colitis and Crohn's disease, susceptibility locus rs2872507, we have investigated the expression of 13 genes using ileal and colonic biopsies from patients with IBD (inflamed and noninflamed mucosa) or from individuals without IBD (noninflamed mucosa). The susceptibility allele was consistently associated with reduced...

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Identifiers

PMID: 26484354
DOI: 10.1155/2015/834805
PMCID: PMC4592899

Genes

GSDMA
GSDMB
PGAP3
CSF3
ERBB2
GRB7
IKZF3
ZPBP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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