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Article

Associating Multivariate Quantitative Phenotypes with Genetic Variants in Family Samples with a Novel Kernel Machine Regression Method.

Genetics - 1 Dec 2015

Yan Qi, Weeks Daniel E, Celedón Juan C, Tiwari Hemant K, Li Bingshan, Wang Xiaojing, Lin Wan-Yu, Lou Xiang-Yang, Gao Guimin, Chen Wei, Liu Nianjun

Abstract excerpt

The recent development of sequencing technology allows identification of association between the whole spectrum of genetic variants and complex diseases. Over the past few years, a number of association tests for rare variants have been developed. Jointly testing for association between genetic variants and multiple correlated phenotypes may increase the power to detect causal genes in family-based studies, but...

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Identifiers

PMID: 26482791
DOI: 10.1534/genetics.115.178590
PMCID: PMC4676518

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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