Article
Novel Methods for Family-Based Genetic Studies.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Yan Qi
Abstract excerpt
The recent development of microarray and sequencing technology allows identification of disease susceptibility genes. Although the genome-wide association studies (GWAS) have successfully identified many genetic markers related to human diseases, the traditional statistical methods are not powerful to detect rare genetic markers. The rare genetic markers are usually grouped together and tested at the set level....
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