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Article

High‐resolution array CGH identifies common mechanisms that drive embryonal rhabdomyosarcoma pathogenesis

15 Mar 2011

Abstract excerpt

Pediatric rhabdomyosarcoma occurs as two biologically distinct histological variants, embryonal (ERMS) and alveolar (ARMS). To identify genomic changes that drive ERMS pathogenesis, we used a new array comparative genomic hybridization (aCGH) platform to examine a specific subset of ERMS tumors, those occurring in children with clinically defined intermediate-risk disease. The aCGH platform used has an average...

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PMID: 21412928
DOI: 10.1002/gcc.20864

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