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Article

Methylation profiling reveals novel molecular classes of rhabdomyosarcoma.

Scientific reports - 15 Nov 2021

Clay Michael R, Patel Anand, Tran Quynh, Hedges Dale J, Chang Ti-Cheng, Stewart Elizabeth, Charville Greg, Cline Cynthia, Dyer Michael A, Orr Brent A

Abstract excerpt

Rhabdomyosarcomas (RMS) represent a family of aggressive soft tissue sarcomas that present in both children and adults. Pathologic risk stratification for RMS has been based on histologic subtype, with poor outcomes observed in alveolar rhabdomyosarcoma (ARMS) and the adult-type pleomorphic rhabdomyosarcoma (PRMS) compared to embryonal rhabdomyosarcoma (ERMS). Genomic sequencing studies have expanded the spectrum...

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Identifiers

PMID: 34782706
DOI: 10.1038/s41598-021-01649-w
PMCID: PMC8592993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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