Article
DNA-binding proteins from marine bacteria expand the known sequence diversity of TALE-like repeats.
Nucleic acids research - 16 Nov 2015
de Lange Orlando, Wolf Christina, Thiel Philipp, Krüger Jens, Kleusch Christian, Kohlbacher Oliver, Lahaye Thomas
Abstract excerpt
Transcription Activator-Like Effectors (TALEs) of Xanthomonas bacteria are programmable DNA binding proteins with unprecedented target specificity. Comparative studies into TALE repeat structure and function are hindered by the limited sequence variation among TALE repeats. More sequence-diverse TALE-like proteins are known from Ralstonia solanacearum (RipTALs) and Burkholderia rhizoxinica (Bats), but RipTAL and...
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