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Article

A TAL effector repeat architecture for frameshift binding.

Nature communications - 11 Mar 2014

Richter Annekatrin, Streubel Jana, Blücher Christina, Szurek Boris, Reschke Maik, Grau Jan, Boch Jens

Abstract excerpt

Transcription activator-like effectors (TALEs) are important Xanthomonas virulence factors that bind DNA via a unique tandem 34-amino-acid repeat domain to induce expression of plant genes. So far, TALE repeats are described to bind as a consecutive array to a consecutive DNA sequence, in which each repeat independently recognizes a single DNA base. This modular protein architecture enables the design of any...

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PMID: 24614980
DOI: 10.1038/ncomms4447

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