Article

PrediTALE: A novel model learned from quantitative data allows for new perspectives on TALE targeting

2019-01-17

Abstract excerpt

Plant-pathogenic Xanthomonas bacteria secret transcription activator-like effectors (TALEs) into host cells, where they act as transcriptional activators on plant target genes to support bacterial virulence. TALEs have a unique modular DNA-binding domain composed of tandem repeats. Two amino acids within each tandem repeat, termed repeat-variable diresidues, bind to contiguous nucleotides on the DNA sequence and...

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Literature Corpus work: dd30f25d-576f-53b5-8726-e1dcd855e8e4
DOI: 10.1101/522458

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