Article
Repeat 1 of TAL effectors affects target specificity for the base at position zero.
Nucleic acids research - 1 Jun 2014
Schreiber Tom, Bonas Ulla
Abstract excerpt
AvrBs3, the founding member of the Xanthomonas transcription-activator-like effectors (TALEs), is translocated into the plant cell where it localizes to the nucleus and acts as transcription factor. The DNA-binding domain of AvrBs3 consists of 17.5 nearly-identical 34 amino acid-repeats. Each repeat specifies binding to one base in the target DNA via amino acid residues 12 and 13 termed repeat variable diresidue...
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