Article
Associations between single nucleotide polymorphisms in the FAS pathway and acute kidney injury.
Critical care (London, England) - 19 Oct 2015
Bhatraju Pavan, Hsu Christine, Mukherjee Paramita, Glavan Bradford J, Burt Amber, Mikacenic Carmen, Himmelfarb Jonathan, Wurfel Mark
Abstract excerpt
INTRODUCTION: To determine whether single nucleotide polymorphisms (SNPs) in FAS and related genes are associated with acute kidney injury (AKI) in patients with acute respiratory distress syndrome (ARDS). METHODS: We studied 401 (Caucasian N = 310 and African-American N = 91) patients aged ≥ 13 years with ALI who enrolled in the Fluid and Catheter Treatment Trial (FACTT) between 2000 and 2005 from 20 North...
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