Article
Further investigation in europeans of susceptibility variants for polycystic ovary syndrome discovered in genome-wide association studies of Chinese individuals.
The Journal of clinical endocrinology and metabolism - 1 Jan 2015
Brower Meredith A, Jones Michelle R, Rotter Jerome I, Krauss Ronald M, Legro Richard S, Azziz Ricardo, Goodarzi Mark O
Abstract excerpt
CONTEXT: Two genome-wide association studies (GWAS) of polycystic ovary syndrome (PCOS) have identified 11 susceptibility loci in Chinese individuals. Some of the risk loci identified in Chinese cohorts, mostly from the first GWAS, have been replicated in Europeans. Replication of the loci from the second GWAS in European cohorts is necessary to determine whether the same variants confer risk for PCOS in multiple...
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