Article
Blood oxidative stress and metallothionein expression in Rett syndrome: Probing for markers.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Apr 2016
Pintaudi Maria, Veneselli Edvige, Voci Adriana, Vignoli Aglaia, Castiglione Dora, Calevo Maria Grazia, Grasselli Elena, Ragazzoni Milena, Cogliati Francesca, Calzari Luciano, Scornavacca Giulia Federica, Russo Silvia, Vergani Laura
Abstract excerpt
OBJECTIVES: Oxidative stress seems to be involved in Rett syndrome (RTT). The aim of this study was to assess the antioxidant status in RTT children with MECP2 gene mutations with respect to healthy controls, and to explore novel blood antioxidant markers for RTT severity. METHODS: In erythrocytes from RTT females aged 2-14 years (n = 27) and age-matched controls (n = 27), we measured the levels of malonaldehyde...
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