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Article

Oxidative stress in Rett syndrome: natural history, genotype, and variants.

Redox report : communications in free radical research - 1 Jan 2011

Leoncini Silvia, De Felice Claudio, Signorini Cinzia, Pecorelli Alessandra, Durand Thierry, Valacchi Giuseppe, Ciccoli Lucia, Hayek Joussef

Abstract excerpt

OBJECTIVES: Rett syndrome (RTT) is an X-linked autism spectrum disorder caused by mutations in the MeCP2 gene in the great majority of cases. Evidence suggests a potential role of oxidative stress (OS) in its pathogenesis. Here, we investigated the potential value of OS markers (non-protein-bound iron (NPBI) and F2-isoprostanes (F2-IsoPs)) in explaining natural history, genotype-phenotype correlation, and...

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Source

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Identifiers

PMID: 21888765
DOI: 10.1179/1351000211Y.0000000004
PMCID: PMC6837451

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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