Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson's disease.

doi:10.1016/j.envres.2015.08.022

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Article

Genetic variability in ABCB1, occupational pesticide exposure, and Parkinson's disease.

Environmental research - 1 Nov 2015

Narayan Shilpa, Sinsheimer Janet S, Paul Kimberly C, Liew Zeyan, Cockburn Myles, Bronstein Jeff M, Ritz Beate

Abstract excerpt

BACKGROUND: Studies suggested that variants in the ABCB1 gene encoding P-glycoprotein, a xenobiotic transporter, may increase susceptibility to pesticide exposures linked to Parkinson's Disease (PD) risk. OBJECTIVES: To investigate the joint impact of two ABCB1 polymorphisms and pesticide exposures on PD risk. METHODS: In a population-based case control study, we genotyped ABCB1 gene variants at rs1045642...

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Identifiers

PMID: 26457621
DOI: 10.1016/j.envres.2015.08.022
PMCID: PMC4911423

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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