Article
Dopamine transporter genetic variants and pesticides in Parkinson's disease.
Environmental health perspectives - 1 Jun 2009
Ritz Beate R, Manthripragada Angelika D, Costello Sadie, Lincoln Sarah J, Farrer Matthew J, Cockburn Myles, Bronstein Jeff
Abstract excerpt
BACKGROUND: Research suggests that independent and joint effects of genetic variability in the dopamine transporter (DAT) locus and pesticides may influence Parkinson's disease (PD) risk. MATERIALS: METHODS: In 324 incident PD patients and 334 population controls from our rural California case-control study, we genotyped rs2652510, rs2550956 (for the DAT 5' clades), and the 3' variable number of tandem repeats...
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