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Article

A haplotype of the methylenetetrahydrofolate reductase gene predicts poor tumor response in rectal cancer patients receiving preoperative chemoradiation.

Pharmacogenetics and genomics - 1 Nov 2006

Terrazzino Salvatore, Agostini Marco, Pucciarelli Salvatore, Pasetto Lara Maria, Friso Maria Luisa, Ambrosi Alessandro, Lisi Veronica, Leon Alberta, Lise Mario, Nitti Donato

Abstract excerpt

OBJECTIVE: The objective of the present study was to evaluate whether germline methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms as well as polymorphisms in the thymidylate synthase gene promoter, namely the variable number tandem repeat polymorphism (TS VNTR) and the int...

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Source

Identifiers

PMID: 17047490
DOI: 10.1097/01.fpc.0000230412.89973.c0

Genes

MTHFR
TRG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17047490-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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