Article
Macrophages, meta-inflammation, and immuno-metabolism.
TheScientificWorldJournal - 1 Jan 2011
Shapiro Haim, Lutaty Aviv, Ariel Amiram
Abstract excerpt
Current research depicts specific modes of immunity and energy metabolism as being interrelated at the molecular, cellular, organ and organism level. Hence, whereas M2 (alternatively-activated) macrophages dominate insulin-sensitive adipose tissue in the lean, M1-skewed (classically-activated) macrophages accumulate in parallel to adiposity in the obese, and promote inflammation and insulin resistance, that is,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
