Article
Functional Analysis of the Exocyst Subunit Sec15 in Candida albicans.
Eukaryotic cell - 1 Dec 2015
Chavez-Dozal Alba A, Bernardo Stella M, Rane Hallie S, Lee Samuel A
Abstract excerpt
In prior studies of exocyst-mediated late secretion in Candida albicans, we have determined that Sec6 contributes to cell wall integrity, secretion, and filamentation. A conditional mutant lacking SEC6 expression exhibits markedly reduced lateral hyphal branching. In addition, lack of the related t-SNAREs Sso2 and Sec9 also leads to defects in secretion and filamentation. To further understand the role of the...
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