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Article

Contact dermatitis in the construction industry: the role of filaggrin loss-of-function mutations.

The British journal of dermatology - 1 Feb 2016

Timmerman J G, Heederik D, Spee T, van Rooy F G, Krop E J M, Koppelman G H, Rustemeyer T, Smit L A M

Abstract excerpt

BACKGROUND: A high prevalence of contact dermatitis (CD) and respiratory symptoms has been observed in the construction industry, probably due to widespread exposure to irritants and allergens. It is unknown whether carriers of loss-of-function mutations in the gene encoding filaggrin (FLG), a known risk gene for eczema and asthma, are at increased risk. OBJECTIVES: To investigate associations of FLG mutations...

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Source

Identifiers

PMID: 26451970
DOI: 10.1111/bjd.14215

Genes

FLG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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