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Article

No remarkable differences in rates of sensitization to common type I and IV allergens between FLG loss-of-function mutation carriers and wild-type subjects.

Contact dermatitis - 1 Jan 2014

Landeck Lilla, Visser Maaike, Skudlik Christoph, Brans Richard, Kezic Sanja, John Swen Malte

Abstract excerpt

BACKGROUND: Loss-of-function mutations in the filaggrin gene (FLG) have been associated with reduced skin barrier function, possibly allowing increased penetration of irritants and allergens. OBJECTIVES: To study whether FLG loss-of-function mutation carriers show different rates of sensitization to common type I and IV allergens among patients referred for occupational contact dermatitis of the hands. MATERIALS...

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Source

Identifiers

PMID: 23848345
DOI: 10.1111/cod.12109

Genes

FLG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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