Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of growth phase feeding strategies on succinate production by metabolically engineered Escherichia coli.

Applied and environmental microbiology - 1 Feb 2010

Jiang Min, Liu Shu-Wen, Ma Jiang-Feng, Chen Ke-Quan, Yu Li, Yue Fang-Fang, Xu Bing, Wei Ping

Abstract excerpt

Aerobic growth conditions significantly influenced anaerobic succinate production in two-stage fermentation by Escherichia coli AFP111 with knockouts in rpoS, pflAB, ldhA, and ptsG genes. At a low cell growth rate limited by glucose, enzymes involved in the reductive arm of the tricarboxylic acid cycle and the glyoxylate shunt showed elevated activities, providing AFP111 with intracellular redox balance and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aerobiosis
Share to Anaerobiosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Citric Acid Cycle

Share to Fermentation

Share to Glyoxylates

Share to Phosphoenolpyruvate Sugar Phosphotransferase System

Share to Sigma Factor

Share to Succinic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 20038712
DOI: 10.1128/AEM.02190-09
PMCID: PMC2820960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of growth phase feeding strategies on succinate production by metabolically engineered Escherichia coli.PMID 20038712Read ↗

High-yield anaerobic succinate production by strategically regulating multiple metabolic pathways based on stoichiometric maximum in Escherichia coli.Semantic proximity Read ↗

Comparative fluxome and metabolome analysis for overproduction of succinate in Escherichia coli.Semantic proximity Read ↗

Metabolic engineering of Escherichia coli and in silico comparing of carboxylation pathways for high succinate productivity under aerobic conditions.Semantic proximity Read ↗

Model-aided atpE gene knockout strategy in Escherichia coli for enhanced succinic acid production from glycerol.Semantic proximity Read ↗

Enhanced succinic acid production under acidic conditions by introduction of glutamate decarboxylase system in E. coli AFP111.Semantic proximity Read ↗

Directed pathway evolution of the glyoxylate shunt in Escherichia coli for improved aerobic succinate production from glycerol.Semantic proximity Read ↗

Chemostat culture characterization of Escherichia coli mutant strains metabolically engineered for aerobic succinate production: a study of the modified metabolic network based on metabolite profile, enzyme activity, and gene expression profile.Semantic proximity Read ↗

Characterization of E. coli MG1655 and frdA and sdhC mutants at various aerobiosis levels.Semantic proximity Read ↗

Metabolic evolution of energy-conserving pathways for succinate production in Escherichia coli.Semantic proximity Read ↗

Homolactate fermentation by metabolically engineered Escherichia coli strains.Semantic proximity Read ↗

High glycolytic flux improves pyruvate production by a metabolically engineered Escherichia coli strain.Semantic proximity Read ↗

Escherichia coli genome-scale metabolic gene knockout of lactate dehydrogenase (ldhA), increases succinate production from glycerol.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.