Article
Metabolic analysis of Corynebacterium glutamicum during lactate and succinate productions under oxygen deprivation conditions.
Journal of molecular microbiology and biotechnology - 1 Jan 2004
Inui Masayuki, Murakami Shikiko, Okino Shohei, Kawaguchi Hideo, Vertès Alain A, Yukawa Hideaki
Abstract excerpt
Lactate and succinate were produced from glucose by Corynebacterium glutamicum under oxygen deprivation conditions without growth. Addition of bicarbonate to the reaction mixture led not only to a 3.6-fold increase in succinate production rate, but also to a 2.3- and 2.5-fold increase, respectively, of the rates of lactate production and glucose consumption, compared to the control. Furthermore, when small...
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