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Article

Human adipose tissue macrophages display activation of cancer-related pathways.

The Journal of biological chemistry - 22 Jun 2012

Mayi Thérèse Hérvée, Daoudi Mehdi, Derudas Bruno, Gross Barbara, Bories Gael, Wouters Kristiaan, Brozek John, Caiazzo Robert, Raverdi Violeta, Pigeyre Marie, Allavena Paola, Mantovani Alberto, Pattou François, Staels Bart, Chinetti-Gbaguidi Giulia

Abstract excerpt

Obesity is associated with a significantly increased risk for cancer suggesting that adipose tissue dysfunctions might play a crucial role therein. Macrophages play important roles in adipose tissue as well as in cancers. Here, we studied whether human adipose tissue macrophages (ATM) modulate cancer cell function. Therefore, ATM were isolated and compared with monocyte-derived macrophages (MDM) from the same...

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Share to Adipocytes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22511784
DOI: 10.1074/jbc.M111.315200
PMCID: PMC3381151

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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