Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Osteoclast stimulatory transmembrane protein induces a phenotypic switch in macrophage polarization suppressing an M1 pro-inflammatory state.

Acta biochimica et biophysica Sinica - 1 Oct 2017

Yuan Huimin, He Jiangping, Zhang Guangya, Zhang Dandan, Kong Xiangxin, Chen Fengling

Abstract excerpt

Macrophages are the key cells in metabolic syndrome and are also a risk factor for metabolic disease. Macrophages have different functions and transcriptional profiles, but all are required for maintaining homeostasis. It is well known that macrophages play a key role in inflammation and early atherogenesis, and are present in two phenotypes: pro-inflammatory (M1) and anti-inflammatory (M2). Osteoclast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammation Mediators
Share to Interleukin-4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipopolysaccharides

Share to Macrophage Activation

Share to RAW 264.7 Cells

Share to STAT1 Transcription Factor

Share to STAT6 Transcription Factor

Share to THP-1 Cells

Source

Identifiers

PMID: 28981605
DOI: 10.1093/abbs/gmx092

Genes

STAT6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Osteoclast stimulatory transmembrane protein induces a phenotypic switch in macrophage polarization suppressing an M1 pro-inflammatory state.PMID 28981605Read ↗

SOCS molecules: the growing players in macrophage polarization and functionSemantic proximity Read ↗

STAT6 Upregulation Promotes M2 Macrophage Polarization to Suppress Atherosclerosis.Semantic proximity Read ↗

Advances in the role of STAT3 in macrophage polarizationSemantic proximity Read ↗

Contribution of Macrophage Polarization to Metabolic Diseases.Semantic proximity Read ↗

Regulation of Macrophage Activation and Differentiation in AtherosclerosisSemantic proximity Read ↗

P311 Curtails Inflammation Through M2-Type Polarization of Macrophages and Potentially via Gut Microbiome ModulationSemantic proximity Read ↗

The Role of Autophagy and Macrophage Polarization in the Process of Chronic Inflammation and RegenerationSemantic proximity Read ↗

TSC1 controls macrophage polarization to prevent inflammatory diseaseSemantic proximity Read ↗

Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis.Semantic proximity Read ↗

Macrophage Polarization in Atherosclerosis.Semantic proximity Read ↗

The Role of Macrophages in Atherosclerosis: Pathophysiologic Mechanisms and Treatment Considerations.Semantic proximity Read ↗

The markers to delineate different phenotypes of macrophages related to metabolic disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.