Article
Hof1 plays a checkpoint-related role in MMS-induced DNA damage response in Candida albicans.
Molecular biology of the cell - 1 Mar 2020
Feng Jinrong, Islam Amjad, Bean Bjorn, Feng Jia, Sparapani Samantha, Shrivastava Manjari, Goyal Aashima, Omran Raha Parvizi, Mallick Jaideep, Whiteway Malcolm
Abstract excerpt
Cells depend on robust DNA damage recognition and repair systems to maintain genomic integrity for survival in a mutagenic environment. In the pathogenic yeast Candida albicans, a subset of genes involved in the response to DNA damage-induced genome instability and morphological changes has been found to regulate virulence. To better understand the virulence-linked DNA repair network, we screened for methyl...
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