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Article

GCKR and PPP1R3B identified as genome-wide significant loci for plasma lactate: the Atherosclerosis Risk in Communities (ARIC) study.

Diabetic medicine : a journal of the British Diabetic Association - 1 Jul 2016

Tin A, Balakrishnan P, Beaty T H, Boerwinkle E, Hoogeveen R C, Young J H, Kao W H L

Abstract excerpt

AIM: To investigate the genetic influence of circulating lactate level, a marker of oxidative capacity associated with diabetes. METHODS: We conducted a genome-wide association study of log-transformed plasma lactate levels in 6901 European-American participants in the Atherosclerosis Risk in Communities study. For regions that achieved genome-wide significance in European-American participants, we conducted...

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Source

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Identifiers

PMID: 26433129
DOI: 10.1111/dme.12971
PMCID: PMC4819009

Genes

GCKR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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